Malignant Pheochromocytoma with Liver Metastasis Treated by Transcatheter Arterial Chemo-Embolization (TACE)

Satoshi Hidaka; Atsushi Hiraoka; Hironori Ochi; Takahide Uehara; Tomoyuki Ninomiya; Yasunao Miyamoto; Aki Hasebe; Tetsuya Tanihira; Atsushi Tanabe; Misa Ichiryu; Hiromasa Nakahara; Nayu Tazuya; Iku Ninomiya; Kojiro Michitaka

doi:10.2169/internalmedicine.49.3061

CASE REPORTS

Malignant Pheochromocytoma with Liver Metastasis Treated by Transcatheter Arterial Chemo-Embolization (TACE)

Satoshi Hidaka, Atsushi Hiraoka, Hironori Ochi, Takahide Uehara, Tomoyuki Ninomiya, Yasunao Miyamoto, Aki Hasebe, Tetsuya Tanihira, Atsushi Tanabe, Misa Ichiryu, Hiromasa Nakahara, Nayu Tazuya, Iku Ninomiya, Kojiro Michitaka

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Keywords: TACE, malignant pheochromocytoma, liver metastasis, doxazosin, phentolamine

JOURNAL OPEN ACCESS

2010 Volume 49 Issue 7 Pages 645-651

DOI https://doi.org/10.2169/internalmedicine.49.3061

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Abstract

Multiple liver metastatic lesions were shown by computed tomography and scintigraphy with 123I- metaiodobenzylguanidine (MIBG) in a 76-year-old woman 2 years after resection of a pheochromocytoma of the right adrenal gland. Transcatheter arterial chemo-embolization (TACE) was performed for the liver metastasis, with blood pressure strictly controlled by administration of doxazosin and phentolamine for the prevention of hypertensive crisis after TACE. There were no severe adverse events associated with the treatment, and the number and size of the lesions were decreased. TACE with strict blood pressure control was an effective and safe therapy for multiple liver metastatic lesions related to malignant pheochromocytoma.

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