Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Hematological Diseases
Successful Treatment of Diffuse Large B-cell Lymphoma Following Waldenström’s Macroglobulinemia with CHOP Chemotherapy Followed by Combination Therapy of CHOP with Rituximab
Keita UCHINO, Hidekazu SAMESHIMA, Toshihiro MIYAMOTO, Tadafumi IINO, Koji KATO, Hideho HENZAN, Ken-ichi AOKI, Koji NAGAFUJI, Hisashi GONDO, Mine HARADA
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Keywords: macroglobulinemia, diffuse large B-cell lymphoma, rituximab, CHOP
JOURNAL OPEN ACCESS

2004 Volume 43 Issue 2 Pages 131-134

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Abstract

We report a 72-year-old man with Waldenström’s macroglobulinemia (WM) in whom diffuse large B-cell lymphoma (DLCL) occurred 17 years after the diagnosis of WM. The malignant cells of both DLCL and WM expressed CD20 on their surface. CHOP plus anti-CD20 monoclonal antibody, rituximab, were effective for both diseases, and the patient remains disease-free 17 months later.

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© 2004 by The Japanese Society of Internal Medicine
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