Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
An Adult Case of Multiple Squamous Papillomas of the Trachea Associated with Human Papilloma Virus Type 6
Hideki ShibuyaTomoko KutomiKosei KujimeKei HaraTetsuya Hisada
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JOURNAL OPEN ACCESS

2008 Volume 47 Issue 17 Pages 1535-1538

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Abstract

A 72-year-old woman with primary biliary cirrhosis complained of dry cough and wheezing. Chest computed tomography showed a tumor arising from the posterior wall of the trachea. Bronchoscopic examination revealed that the tumor was cauliflower-like, with two small polypoid tumors. They were diagnosed as multiple squamous papillomas. The main tumor was recurrent and removed by repeated microwave coagulation therapy (MCT) through bronchoscopy, whereas the two polypoid tumors were likely to disappear spontaneously. Human papilloma virus (HPV) type 6 DNA was detected in the tumor by polymerase chain reaction (PCR) amplification, suggesting that this virus was the cause of her papillomas.

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© 2008 by The Japanese Society of Internal Medicine
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