Hepatic Hemodynamics and Elevation of Liver Stiffness as Possible Predictive Markers of Late-onset Hepatic Failure

Keisuke Kakisaka; Hidekatsu Kuroda; Tamami Abe; Yuji Suzuki; Yuichi Yoshida; Kojiro Kataoka; Yasuhiro Miyamoto; Kazuyuki Ishida; Yasuhiro Takikawa

doi:10.2169/internalmedicine.55.5945

CASE REPORTS

Hepatic Hemodynamics and Elevation of Liver Stiffness as Possible Predictive Markers of Late-onset Hepatic Failure

Keisuke Kakisaka, Hidekatsu Kuroda, Tamami Abe, Yuji Suzuki, Yuichi Yoshida, Kojiro Kataoka, Yasuhiro Miyamoto, Kazuyuki Ishida, Yasuhiro Takikawa

Author information

Keisuke Kakisaka
Division of Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Japan
Hidekatsu Kuroda
Division of Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Japan
Tamami Abe
Division of Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Japan
Yuji Suzuki
Division of Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Japan
Yuichi Yoshida
Division of Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Japan
Kojiro Kataoka
Division of Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Japan
Yasuhiro Miyamoto
Division of Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Japan
Kazuyuki Ishida
Department of Molecular Diagnostic Pathology, Iwate Medical University School of Medicine, Japan
Yasuhiro Takikawa
Division of Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Japan

Keywords: LOHF, resistance index

JOURNAL OPEN ACCESS

2016 Volume 55 Issue 9 Pages 1091-1095

DOI https://doi.org/10.2169/internalmedicine.55.5945

Details

Abstract

A 52-year-old Japanese woman admitted to our hospital for the treatment of liver dysfunction due to an undetermined cause developed disorientation on the 58th hospital day and was diagnosed with late-onset liver failure. Abdominal ultrasound examinations were performed several times from the admission. Before the disorientation appeared, the results of the examinations revealed that the portal flow decreased, after which the hepatic arterial flow increased and the degree of liver stiffness became elevated. Although the pathophysiology of these changes remains unclear, hemodynamic changes and elevation of liver stiffness might be predictive markers of severe liver tissue damage.

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