2022 年 30 巻 1 号 p. 28-32
Primary hepatic neuroendocrine carcinoma is a sporadic tumor. It is challenging to differentiate from other hepatic tumors such as cholangiocarcinoma, hepatocellular carcinoma, and other focal hepatic lesions based on diagnostic imaging results. A 66-year-old woman was referred for evaluation of a hepatic mass discovered on an incidentally abdominal ultrasound. The findings from computed tomography led to a diagnosis of hepatocellular carcinoma, while magnetic resonance imaging results suggested fibrolamellar hepatocellular carcinoma or focal nodular hyperplasia. A partial hepatectomy was performed, and the tumor was removed entirely. Pathology diagnosed a malignant neoplasm of unknown type, and immunohistochemistry confirmed a grade 2 neuroendocrine tumor. Adjuvant chemotherapy was not required after surgery. This case highlights that the diagnosis of primary hepatic neuroendocrine carcinoma remains a challenge that needs to distinguish from other focal liver lesions and differentiate from a secondary metastatic neuroendocrine tumor.
