1996 年 5 巻 1 号 p. 15-18
We investigated the prognostic significance of intraoperative lavage cytology in 276 patients with gastric carcinoma.
Lavage cytology was positive in 18.1% of all patients. The degree of serosal invasion and the area of serosal invasion were closely related to the frequency of positive cytology. Poorly differentiated carcinoma was associated with a significantly higher incidence of positive cytology than well differentiated carcinoma. The 5-year survival rate was 65.9% in patients with negative cytology and 5.7% in patients with positive cytology, indicating a very poor prognosis for those with positive cytology.
Multivariate analysis revealed that lavage cytology, serosal invasion, and lymph node metastasis were the most important prognostic factors for gastric carcinoma. In conclusion, the results of peritoneal lavage cytology might contribute to determining the need for postoperative adjuvant therapy.
