Abstract
It is known that fear-related disorder such as post traumatic disorder and panic disorder is disproportionately prevalent in women. To uncover the biological mechanism behind the sex difference is useful for the development of personalized medicine for the disorders. Recently, the number of studies investigating the sex difference in fear has increased. We summarize the recent epidemiological, neuroimaging, and animal behavioral studies investigating the sex difference in fear-related disorder or fear and discuss the factors behind the sex difference in prevalence.
