抄録
Metabolic fate of 14C-carbaryl in silkworm larvae and adults of the black-tipped leafhopper were investigated. Both insects showed different toxic symptoms under topical application with doses of nearly the LD50 value. Silkworm larvae rapidly consumed carbaryl until about 4 hr after application, and the substance which was a dominant metabolite appeared simultaneously and reached the maximum level, one thirds the initial dose of the insecticide, at 3 hr after application. Seven hr later it disappeared. Another metabolite was recognized about one hr after application and continued to exist for 8 hr. Water soluble metabolites were also noted in small amounts, as that of the second metabolite. Whereas in the adults of the black-tipped leafhopper no labeled metabolites ware found with the exception of water soluble substances, and carbaryl continued to remain almost at 50% of the initial dose even 8 hr after application.Relationship between the recovery of motility from toxic damage of silkworm larvae and the metabolic fate of carbaryl in the silkworm was discussed.
