The relationships of sex hormone binding globulin (SHBG) with high density lipoprotein cholesterol (HDL-C) and fasting insulin (IRI) were investigated in healthy employed men (n=235). In simple correlation analysis, the SHBG was positively related to total cholesterol and HDL-C, and negatively related to IRI. There were no relationships among SHBG, triglyceride and fasting blood glucose. In multiple linear regression analysis, SHBG was one of determi-nant of HDL-C, but not IRI. From these results, it was suggested that SHBG was one of the determinants of HDL-C Ievel in healthy men.
