Abstract
The effect of physical training on cholesterol metabolism was investigated using maleWistar rats fed on a high-fat diet.The diet contained 25.0% casein, 38.15% sucrose, 5.0%minerals, 30.0% lard, 1.7% vitamin mixture, and 0.15% choline chloride.The rats, 5-6 weeksof age, were trained for 3, 6, and 10 weeks according to a treadmill running program.Itconsisted of running at 12 m/min for 60 min/day on 6 days/week.The results obtained are as follows.1.The level of serum cholesterol in the trained rats showed a tendency to be lower than thatin the untrained and control rats.2.The similar tendency was also observed in the amount of liver cholesterol as well.3.The trained rats showed a significant enhancement in the synthesis of cholesterol in liver, being more apparent with longer training.The findings in the present study coincide with those previously observed in the similarexperiment using rats fed on a regular diet, and it has been concluded that physical trainingimproves the cholesterol metabolism under high-fat nutrition to bring a favorable effect on theprophylaxis for arteriosclerosis and many subsequent disturbances.
