抄録
Ventilatory response to carbon dioxide in the summer and winter was measured on healthy 9 male subjects by means of CO2 rebreathing method; the subject rebreathed a gas mixture (about 7% CO2 in O2) of 6 liters for 4 min after the subjects rested in a sitting position for about 20 min. During rebreathing, CO2 concentration of expired air and tidal volume were determined continuously using an infrared CO2, analyzer and respirometer, respectively. The mean and standard deviations for the slope of the ventilatory response line in the summer and winter were 2.42i±0.75 and 2.45±1.03 1·min1'mmHg1. There were no significant differences in the slope of hypercapnic ventilatory response in the summer and winter. However, ventilation corresponding to alveolar CO2 pressure of 60mmHg calculated from regression equation of ventilatory response line were 35.2±15.6 in summer and 25.4±15.2 1·min1 in winter, the difference being significant.