Department of Internal Medicine, Seoul National University College of Medicine Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center
Mi-Yeong Kim
Department of Internal Medicine, Seoul National University College of Medicine Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center
Sung-Yoon Kang
Department of Internal Medicine, Seoul National University College of Medicine Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center
Woo-Jung Song
Department of Internal Medicine, Seoul National University College of Medicine Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center
Hye-Ryun Kang
Department of Internal Medicine, Seoul National University College of Medicine Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center
Trimebutine maleate [2-dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoic acid] has been demonstrated to be active for relieving abdominal pain and it is widely used for patients with irritable bowel syndrome. Adverse drug reactions are mostly mild and well-tolerated. To our knowledge, only two cases of trimebutine induced hypersensitivity have been reported, and both were delayed type reactions. Here, we report the first case of trimebutine maleate-induced anaphylaxis.
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