2019 年 62 巻 2 号 p. 49-54
The current studies have shown that some menopausal symptoms are due to a reduction in testosterone levels. However, testosterone replacement therapy is not the best option for menopausal women because possible occurrence of side effects due to testosterone replacement therapy cannot be ignored. Therefore, in order to explore a possibility that olfactory exposure to essential oils increase testosterone release in menopausal women, we measured salivary testosterone concentration before and after olfactory stimulation by the essential oils. This experiment was conducted in a laboratory dedicated to odor exposure experiments and in a ventilate laboratory at Nagasaki University. In order to minimize the influence of visual stimuli on the subjects, the room lighting was turned off and light from the outside was shielded by a curtain. Perimenopausal women (n = 15 per essential oil) were exposed first to propylene glycol or dipropylene glycol as a control and then to 1 of 10 essential oils (geranium, rose otto, orange sweet, lavender, neroli, frankincense, jasmine absolute, ylang ylang, roman chamomile, and clary sage) dissolved in propylene glycol or dipropylene at 2 l/min for 20 minutes on each experimental day. We measured the testosterone concentrations in saliva before and after each odor exposure in these perimenopausal women. The results of this study demonstrate that olfactory stimulation by jasmine absolute, roman chamomile, and clary sage essential oils increased salivary testosterone. The clinical significance of this should be examined an empirical study in the future.