Flow Injection with Inhibited Chemiluminescence Method for the Determination of Dopamine Hydrochloride

Abstract

A simple rapid and accurate flow injection inhibitory chemiluminescence method has been developed for the determination of dopamine hydrochloride based on its inhibition of the chemiluminescence from the luminol-potassium hexacyanoferrate(III) system. The linear range of determination is 4.0 × 10^-9 - 4.0 × 10^-7 g ml^-1 for dopamine hydrochloride and the detection limit is 1.14 × 10^-9 g ml^-1. The method has been applied to determine the content of dopamine in pharmaceutical preparation with satisfactory results.