Cetyltrimethylammonium Bromide-Enhanced Chemiluminescence Determination of Uric Acid Using a Luminol-Hexacyanoferrate(III)-Hexacyanoferrate(II) System

Abstract

A chemiluminescence (CL) method using flow injection (FI) was developed for the determination of uric acid based on the enhancement chemiluminescence intensity of luminol-hexacyanoferrate(III)-hexacyanoferrate(II) in the presence of cetyltrimethylammonium bromide and the uric acid species. The linear range was 7.0 × 10^-10 - 9.0 × 10^-7 M with a detection limit (3σ) of 2.58 × 10^-10 M, which was about two orders of magnitude lower than those reported. The proposed method was used for the determination of uric acid in real samples.