Analytical Sciences
Online ISSN : 1348-2246
Print ISSN : 0910-6340
ISSN-L : 0910-6340
Original Papers
Liquid Filling Method for Nanofluidic Channels Utilizing the High Solubility of CO2
Eiichiro TAMAKIAkihide HIBARAHaeng-Boo KIMManabu TOKESHITakeshi OOIMasayuki NAKAOTakehiko KITAMORI
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2006 Volume 22 Issue 4 Pages 529-532


We developed a fabrication method and a liquid filling method for a nano chemical reactor that used Y-shaped nanochannels specially designed for mixing and reacting. In order to reduce the pressure loss and to utilize the characteristics of the nanochannel, inlet microchannels were fabricated just beside the nanochannels. We investigated an initial liquid filling method into the nanochannels that ensured there were no air bubbles that could cause a flow stack due to the capillary pressure. In our method, the micro- and nanochannels were filled with carbon dioxide and any remaining air during the initial liquid introduction was dissolved utilizing the high solubility of carbon dioxide. We propose that chemical reactions in nanospaces can be realized by utilizing these fabrication and liquid introduction techniques.

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© 2006 by The Japan Society for Analytical Chemistry
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