Analytical Sciences
Online ISSN : 1348-2246
Print ISSN : 0910-6340
ISSN-L : 0910-6340
Notes
Release Mechanism from a Microsphere of a Silkworm Chitin Derivative Studied by Single Microparticle Injection and Absorption Microspectroscopy
Kiyoharu NAKATANIYoshiyuki KOBAYASHIAtsunobu HAGA
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2008 Volume 24 Issue 5 Pages 677-680

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Abstract
The release process of phenol blue from a dibutyrylchitin microsphere, prepared with chitin from a silkworm, into an aqueous solution was kinetically analyzed by single microparticle injection/manipulation and absorption microspectroscopy. The distribution ratio and the release rate of phenol blue in the single microsphere/water system were significantly influenced by the pH of the solution. These results are discussed in terms of the protonation of phenol blue and dibutyrylchitin, and the pore and surface diffusion in the pores of the microsphere.
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© 2008 by The Japan Society for Analytical Chemistry
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