Visual Assay of Total Iron in Human Serum with Bathophenanthrolin Disulfonate-accommodated MCM-41

Misato SAKAMOTO; Keita HIZAWA; Manabu HOSAKA; Masao SUGAWARA

doi:10.2116/analsci.32.241

Notes

Visual Assay of Total Iron in Human Serum with Bathophenanthrolin Disulfonate-accommodated MCM-41

Misato SAKAMOTO, Keita HIZAWA, Manabu HOSAKA, Masao SUGAWARA

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Keywords: Mesoporous silica, visual determination, bathophenanthroline disulfonate, iron(II) in serum

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Supplementary material

2016 Volume 32 Issue 2 Pages 241-244

DOI https://doi.org/10.2116/analsci.32.241

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Abstract

A simple visual method for determining the total iron in human serum is proposed based on color development in the nanospace of mesoporous silica MCM-41 and a chromogenic ligand bathophenathroline disulfonate (BPS). Observing the color intensity of a complex between iron(II) and BPS devloped on the MCM-41 material by the naked eye enabled us to quntify iron(II) with a detection limit of 0.5 μM. The BPS-loaded MCM-41 was successfully applied for quantifying the total iron in human serum.

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