Abstract
Octadecyl substituted β-cyclodextrin, which was synthesized in DMSO, was dynamically coated on octadecylsilanized (ODS) silica through hydrophobic interaction. This type of immobilization is readily feasible, not being accompanied by any chemical reactions. The dynamically coated β-cyclodextrin stationary phase was used for liquid chromatographic separation of the geometrical isomers of substituted phenols. The chromatographic property of the coated β-cyclodextrin column was different from that of the ODS column. Its separation efficiency for the phenols was greater than that of the ODS column.
