Structure of Flurandrenolide

Abstract

The title compound, C₂₄H₃₃FO₆, is a glucocorticoid. The crystal belongs to space group C2 with the cell dimensions a = 30.575(2), b = 9.3616(9), c = 17.012(5)Å and β = 120.67(4)°. The final R value is 0.049. There are two crystallographically independent flurandrenolide molecules. The cyclohexenone rings in both molecules adopt different half-chair conformations. The dioxolane rings in both molecules take different puckered forms. The other corresponding rings in both molecules take essentially similar conformations.