Synthesis and Crystal Structure of a Novel Compound: 1-{[2-(1,3-Diphenyl-1H-naphtho [1,2-e][1,3]oxazin-2-yl)cyclohexylamino]phenylmethyl}-naphthalen-2-ol

Abstract

The reaction of (1R,2R)-1,2-diaminocyclohexane with 2-naphthol and benzaldehyde gave the title compound, 1-{[2-(1,3-diphenyl-1H-naphtho[1,2-e][1,3]oxazin-2-yl)cyclohexylamino]phenylme thyl}naphthalen-2-ol (2), under solvent-free condition. The results of an X-ray single crystal analysis indicate that there are five chiral centers and two different types of intramolecular hydrogen bonds in the title compound. One is a O-H…N hydrogen bond, and the other is a N-H…N hydrogen bond.