Analytical Sciences: X-ray Structure Analysis Online
Online ISSN : 1348-2238
ISSN-L : 1348-2238
Part 1
Structure of Trimetazidine
Rumiko TANAKAMasayuki HARAMURAAkito TANAKANoriaki HIRAYAMA
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2005 年 21 巻 p. x3-x4

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抄録
The title compound is an antianginal agent. The crystal, C14H22N2O3·2HCl·1/2H2O, belongs to space group P21/a with cell dimensions of a = 13.139(6), b = 7.452(5), c = 17.991(8)Å, β = 93.20(4)°. The final R value is 0.081. The piperazine ring takes a chair conformation. The dihedral angle between the least-squares planes of the piperazine and phenyl rings is 60.3(6)°. The methylene carbon atom bonded to the phenyl ring is significantly deviated from the plane of the phenyl ring.
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© 2005 by The Japan Society for Analytical Chemistry
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