Analytical Sciences: X-ray Structure Analysis Online
Online ISSN : 1348-2238
ISSN-L : 1348-2238
Part 1
Crystal Structure of a 2:1 Complex of Indomethacin and Lidocaine
Yukiko UMEDAHiromasa NAGASEMizue MAKIMURAKazuo TOMONOMotoo SHIROHaruhisa UEDA
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2007 年 23 巻 p. x15-x16

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Crystals of a 2:1 complex, (Cl9H16ClNO4)2·C14H22N2O, between indomethacin and lidocaine were grown by slow evaporation from an ethanol solution. Two different indomethacin (I and II) molecules showed different conformations. The proton of the carboxyl group of indomethacin II was transferred to an amino group of lidocaine. The intermolecular hydrogen bonds and CH/π interactions were observed.

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© 2007 by The Japan Society for Analytical Chemistry
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