An Assessment of Myocardial Perfusion Count Distribution Differences among Various Image Reconstruction Methods in Myocardial Perfusion Scans Using Three Head Gamma Camera

Abstract

Purpose: The novel 3 Detector SPECT ‘GCA-9300R’ is equipped with attenuation correction algorithm of 3D-OSEM and SSPAC. The combination of this highly sensitive gamma camera with high quality techniques seems very promising concerning diagnostic value. The aim of this study is to comprehend the difference of tracer uptake in MPS under the usage of 3D-OSEM, SSPAC method compared with FBP using triple head gamma camera.
Methods: We examined a total of 40 consecutive cases (20 cases for both male and females), in which conducted myocardial perfusion scans and diagnosed as no heart ischemic state. The examination was conducted under rest first 1-day protocol. Comparative analysis was conducted between FBP and 3D-OSEM (rest and stress), FBP and SSPAC (rest and stress), and FBP and prone images (stress) as well as 3D-OSEM and prone images (stress).
Results: In FBP, we observed a lower count distribution in septal region, higher count distribution in apical region and apical side of the lateral region. 3D-OSEM showed slightly lower count distribution compared with FBP in the septal, lateral and a apical region. The reduction was more prominent with the males. Regarding SSPAC, in comparison with FBP, count elevations were observed in the inferior and septal regions while in the lateral and apical region the count was reduced. There was no statistically significant count difference between SSPAC and prone image in the inferior regions.
Conclusion: With GCA-9300R, 3D-OSEM has the tendency toward count reduction in the septal, lateral and apical regions. On the other hand, SSPAC could reduce the count reduction in sepal and inferior regions toward FBP, and could prove to be a very helpful tool in the diagnosis of ischemia.