Abstract
In patients with suspected coronary artery disease (CAD), an anatomical or functional approach can be used to guide further patient management. Functional techniques are able to assess the presence and extent of myocardial ischemia, whereas coronary computed tomography angiography (CTA) can assess the presence and extent of coronary atherosclerosis. Coronary CTA has a high sensitivity to detect obstructive CAD in patients with a low to intermediate probability and is therefore commonly used to rule out coronary atherosclerosis. To improve its specificity, novel techniques as fractional flow reserve using CT (FFRct) and CT myocardial perfusion imaging (CTP) are emerging. This review will summarize the latest trials that investigated how coronary CTA can be applied in clinical practice and compare this technique to other imaging modalities.
