Takotsubo Syndrome

Changes in Diagnostic Criteria and Role of Nuclear Imaging

Abstract

Takotsubo syndrome (TTS) was first described in 1990. A wide variety of TTS cases have been reported since then; the international consensus has proposed several diagnostic criteria. The current diagnostic system often relies on identifying combinations of subsets of symptoms, or criteria, to define diagnoses. In the recently proposed TTS diagnostic criteria, obstructive coronary syndrome and pheochromocytoma involvement changes. Here, we review the criteria and the role of nuclear imaging in TTS diagnosis and discuss new directions that can provide better information.