The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
STUDIES ON T-2636 ANTIBIOTICS. I
TAXONOMY OF STREPTOMYCES ROCHET VAR. VOLUBILIS VAR. NOV. AND PRODUCTION OF THE ANTIBIOTICS AND AN ESTERASE
EIJI HIGASHIDETAKAESHI FUGONOKAZUNORI HATABNOMOTOO SHIBATA
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1971 Volume 24 Issue 1 Pages 1-12

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Abstract
The characteristics of streptomycete strain No. T-2636 producing antibiotics T-2636A, B, C, D, E, F and Mare given and Streptomyces rochei var. volubilis is proposed as the name for this new taxon. The antibiotics T-2636 A, B, C and D show antibacterial activity against Gram-positive bacteria and antibiotic T-2636 M shows antifungal activity. The production ratio of components A, B, C and D depends on cultural conditions. An esterase produced by the organism hydrolyzes the acetyl group of antibiotic T-2636 A converting it into antibiotic T-2636 C.
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© Japan Antibiotics Research Association
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