The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
TUNICAMYCIN, A NEW ANTIBIOTIC. I
ISOLATION AND CHARACTERIZATION OF TUNICAMYCIN
AKIRA TAKATSUKIKEI ARIMAGAKUZO TAMURA
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1971 年 24 巻 4 号 p. 215-223

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Tunicamycin is a new antiviral antibiotic produced by Streptomyces lysosuperificus, nov. sp. The active substance in culture broth is purified by solvent extraction followed by chromatography on silicic acid. It has a mole- cular weight of about 870. The antibiotic is active against animal and plant viruses, Gram-positive bacteria, yeast and fungi. Tunicamycin is similar in some properties to a few known antibiotics but differs from them in certain special characteristics.

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