The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
STUDIES ON MITOMYCINS. V
SYNTHESIS OF INDOLEQUINONE AND THEIR ACTIVITIES
KINICHI NAKANO, NORIO NISHIYAMA, KEIZO UZU, SHUKUO KINOSHITA
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1971 Volume 24 Issue 7 Pages 435-442

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Abstract

Indolequinones postulated as essential structure for activity of mitomycin were synthesized and examined for their antibacterial activities. Acyl esters of 3-hydroxymethylindole(4, 7)dione showed strong activity against Grampositive bacteria but those of 2-hydroxymethylindolequinone did not.

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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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