A NEW AMINOGLYCOSIDE ANTIBIOTIC COMPLEX-THE SELDOMYCINS I. TAXONOMY, FERMENTATION AND ANTIBACTERIAL PROPERTIES

TAKASHI NARA; MITSUYOSHI YAMAMOTO; SEIGO TAKASAWA; SEIJI SATO; TOMOYASU SATO; ISAO KAWAMOTO; RYO OKACHI; ITARU TAKAHASHI; ATSUKO MORIKAWA

doi:10.7164/antibiotics.30.17

A NEW AMINOGLYCOSIDE ANTIBIOTIC COMPLEX-THE SELDOMYCINS

I. TAXONOMY, FERMENTATION AND ANTIBACTERIAL PROPERTIES

TAKASHI NARA, MITSUYOSHI YAMAMOTO, SEIGO TAKASAWA, SEIJI SATO, TOMOYASU SATO, ISAO KAWAMOTO, RYO OKACHI, ITARU TAKAHASHI, ATSUKO MORIKAWA

著者情報

ジャーナルフリー

1977 年 30 巻 1 号 p. 17-24

DOI https://doi.org/10.7164/antibiotics.30.17

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抄録

A soil isolate named Streptomyces hofunensis sp. nov. was found to produce seldomycin factors 1, 2, 3 and 5, new aminoglycoside antibiotics. Taxonomy of the producing organism, a study of cultural conditions for seldomycin production, and antibacterial activity of seldomycins are reported. Seldomycin factor 5 was the most active both in vitro and in vivo against gram-positive and negative bacteria.

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