The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
CAPSIMYCIN, A NEW ANTIBIOTIC. I PRODUCTION, ISOLATION AND PROPERTIES
SHOJIRO AIZAWAHAJIME AKUTSUTOSHIYUKI SATOMITHIJUKO NAGATSURYUSUKE TAGUCHIAKIO SEINO
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1979 Volume 32 Issue 3 Pages 193-196

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Abstract

Capsimycin is a new antifungal antibiotic produced by a strain of Streptomyces sp. C 49-87. The active substance in the fermented broth was isolated by solvent extraction followed by silica gel column chromatography. The antibiotic melts at 186°C (decomp.) and has a molecular formula C30H40N2O6. It exhibits marked inhibitory activity against Phytophthora capsici (Leaf blight disease of cucumber) and Pythium: debaryamum (Damping-off disease of cucumber).

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© Japan Antibiotics Research Association
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