NEW CEPHALOSPORINS AND 7α-METHOXY CEPHALOSPORINS CHEMISTRY AND BIOLOGICAL ACTIVITIES

GUGLIELMO ELITROPI; EZIO PANTÒ; SILVIA TRICERRI; LINO CHIARANI; ROBERTO PEZZALI; MARIO RIVA; GIOVANNA ZANUSO

doi:10.7164/antibiotics.32.900

GUGLIELMO ELITROPI, EZIO PANTÒ, SILVIA TRICERRI, LINO CHIARANI, ROBERTO PEZZALI, MARIO RIVA, GIOVANNA ZANUSO

著者情報

ジャーナルフリー

1979 年 32 巻 9 号 p. 900-908

DOI https://doi.org/10.7164/antibiotics.32.900

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The synthesis and the in vitro activity of a number of cephalosporins and 7α-methoxy cephalosporins having 7-acyl substituents derived from 1-methyl-4 (or 5)-nitro-1H-imidazolyl-thioacetic acids are described. The microbiological profile is influenced by the position of both the nitro group and the side-chain sulfur atom on the 1-methyl imidazole, and by the nature of the 3-substituent.

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