A NEW AMINOGLYCOSIDE ANTIBIOTIC, SANNAMYCIN C AND ITS 4-N-GLYCYL DERIVATIVE

TAKEO DEUSHI; TAKASHI YAMAGUCHI; KAZUHIRO KAMIYA; AKIO IWASAKI; TOSHIMI MIZOGUCHI; MASAHITO NAKAYAMA; ISAMU WATANABE; HISAKATSU ITOH; TOSHIHITO MORI

doi:10.7164/antibiotics.33.1274

TAKEO DEUSHI, TAKASHI YAMAGUCHI, KAZUHIRO KAMIYA, AKIO IWASAKI, TOSHIMI MIZOGUCHI, MASAHITO NAKAYAMA, ISAMU WATANABE, HISAKATSU ITOH, TOSHIHITO MORI

著者情報

ジャーナルフリー

1980 年 33 巻 11 号 p. 1274-1280

DOI https://doi.org/10.7164/antibiotics.33.1274

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抄録

Streptomyces sannanensis KC-7038 used for the production of sannamycins A and B has also produced another antibiotic sannamycin C, in the culture broth. Physico-chemical characterization revealed that sannamycin C is a new aminoglycoside antibiotic having 6-N-methylpurpurosamine
C and 2-deoxy-3-epi-fortamine. Its 4-N-glycyl derivative indicated inhibitory activity against Gram-positive and Gram-negative bacteria containing aminogly-coside resistant strains.

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