PHYSICO-CHEMICAL PROPERTIES OF NEW ACYL DERIVATIVES OF TYLOSIN PRODUCED BY MICROBIAL TRANSFORMATION

ROKURO OKAMOTO; TSUMORU FUKUMOTO; HIDEO NOMURA; KOHKI KIYOSHIMA; KENJI NAKAMURA; AKIRA TAKAMATSU; HIROSHI NAGANAWA; TOMIO TAKEUCHI

doi:10.7164/antibiotics.33.1300

ROKURO OKAMOTO, TSUMORU FUKUMOTO, HIDEO NOMURA, KOHKI KIYOSHIMA, KENJI NAKAMURA, AKIRA TAKAMATSU, HIROSHI NAGANAWA, TOMIO TAKEUCHI

著者情報

ジャーナルフリー

1980 年 33 巻 11 号 p. 1300-1308

DOI https://doi.org/10.7164/antibiotics.33.1300

詳細

抄録

By microbial transformation of tylosin (I), the following eight new acyl derivatives were obtained: 3-acetyltylosin (II), 3-propionyltylosin (III), 4''-butyryltylosin (IV), 4''-isovaleryltylosin (V), 3-acetyl-4''-butyryltylosin (VI), 3-acetyl-4''-isovaleryltylosin (VII), 3-propionyl-4''-butyryltylosin (VIII) and 3-propionyl-4''-isovaleryltylosin (IX).

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