The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
BIOSYNTHETIC PATHWAY OF 2-DEOXYSTREPTAMINE
TAMIO FUJIWARAEIJI RONDO
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1981 年 34 巻 1 号 p. 13-15

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Four 2-deoxystreptamine (DOS) related compounds including S-11-P, isolated as an intermediate of DOS biosynthesis, were supplemented to the culture of a DOS- mutant of Bacillus circulans. Among the tested aminocyclitol compounds, S-11-P alone was converted to DOS. Addition of other aminocyclitols neither produced antibiotic nor inhibited the incorporation of S-11-P and DOS into butirosins. By these facts, S-11-P was confirmed clearly to be an intermediate of DOS biosynthesis.
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© Japan Antibiotics Research Association
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