STUDIES ON THE OA-6129 GROUP OF ANTIBIOTICS, NEW CARBAPENEM COMPOUNDS
II. IN VITRO EVALUATION
1982 年 35 巻 10 号 p. 1264-1270
詳細
1982 年 35 巻 10 号 p. 1264-1270
The OA-6129 group of antibiotics, new carbapenem compounds, had relatively potent antimicrobial activities against Gram-positive and Gram-negative bacteria. Synergism of compound OA-6129A in combination with conventional β-lactam antibiotics was observed in antimicrobial activity against β-lactamase producers such as Proteus vulgaris GN 76 and Citrobacter freundii GN 346. The new carbapenem compounds were slightly superior to PS-5 in stability to kidney homogenates of various animal species.
