CHRYSCANDIN, A NOVEL PEPTIDYL NUCLEOSIDE ANTIBIOTIC I.TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION

MICHIO YAMASHITA; YASUHISA TSURUMI; JUNJI HOSODA; TADAAKI KOMORI; MASANOBU KOHSAKA; HIROSHI IMANAKA

doi:10.7164/antibiotics.37.1279

CHRYSCANDIN, A NOVEL PEPTIDYL NUCLEOSIDE ANTIBIOTIC

I.TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION

MICHIO YAMASHITA, YASUHISA TSURUMI, JUNJI HOSODA, TADAAKI KOMORI, MASANOBU KOHSAKA, HIROSHI IMANAKA

著者情報

ジャーナルフリー

1984 年 37 巻 11 号 p. 1279-1283

DOI https://doi.org/10.7164/antibiotics.37.1279

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抄録

A novel antifungal antibiotic, chryscandin was found in the culture broth of a strain of fungi. The producing organism was subsequently identified as Chrysosporium pannorum. The antibiotic obtained as colorless needle clystals(C₂₀H₂₃N₇O₆, MW 457)is active against Candida albicans and Gram-positive bacteria, but it is ineffective against filamentous fungi and Gram-negative bacteria. Acute toxicity ls very low in mice.

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