PHENACEIN-AN ANGIOTENSIN-CONVERTING ENZYME INHIBITOR PRODUCED BY A STREPTOMYCETE
II. ISOLATION, STRUCTURE DETERMINATION AND SYNTHESIS
1984 年 37 巻 11 号 p. 1313-1319
詳細
1984 年 37 巻 11 号 p. 1313-1319
Phenacein, an inhibitor of angiotensin-converting enzyme, has been isolated from the fermentation broth of a Streptomyces species belonging to the Streptomyces tanashiensiszaomyceticus group. The inhibitor was shown to be 3, 6-dihydroxy-1-phenazinecarboxylic acid by spectroscopic, degradative and synthetic methods.
