抄録
The in vitro synergism or PS-5 combined with various penicinins and cephalosporins in antimicrobial activity was examined in detail against β-lactam-resistant Gram-negative bacteria. PS-5 showed a highly significant synergism in antimicrobial action against Escherichia coli RGN238 in combination with penicinins; and against Proteus vulgaris GN76 and Serratia marcescens T55 in combination with cephalosporins. It was moderately synergistic against Citrobacter freundii GN346, Enterobacter cloacae 45, Proteus morganii 111 and Enterobacter aerogenes E19, whereas no synergism was observed against Pseudomonas aeruginosa E2 and Klebsiella pneumoniae. 130
