TAKAOKAMYCIN, A NEW PEPTIDE ANTIBIOTIC PRODUCED BYSTREPTOMYCESSP.

Abstract

A new peptide antibiotic named takaokamycin was isolated from a fermentation broth of Streptomycessp. AC-1978, a soil isolate. It exhibits antibacterial activity against some Grampositive bacteria. The molecular weight was found to be 1, 130 on the basis of elemental analysis, FD-mass spectrum and¹H and¹³C NMR. Acid hydrolysate of takaokamycin contains isoleucine, threonine and unidentified amino acids.