CC-1065 TRANSFORMATIONS
1985 年 38 巻 6 号 p. 746-752
詳細
1985 年 38 巻 6 号 p. 746-752
This report defines the transformations that antitumor antibiotic CC-1065 underwent under basic and acidic conditions. The isolation, purification, characterization, and biological properties of a cyclopropapyrroloindole fragment, and an acidic fragment, PDE-I dimer, from a mild alkaline fragmentation and the phenolic product, AAP, resulting from alkylation of acetic acid by the cyclopropyl function are described.
