CLOSTOMICINS, NEW ANTIBIOTICS PRODUCED BY MICROMONOSPORA ECHINOSPORA SUBSP. ARMENIACA SUBSP. NOV. I. PRODUCTION, ISOLATION, AND PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

SATOSHI OMURA; NOBUTAKA IMAMURA; RUIKO OIWA; HIROSHI KUGA; RIMIKO IWATA; ROKURO MASUMA; YUZURU IWAI

doi:10.7164/antibiotics.39.1407

CLOSTOMICINS, NEW ANTIBIOTICS PRODUCED BY MICROMONOSPORA ECHINOSPORA SUBSP. ARMENIACA SUBSP. NOV.

I. PRODUCTION, ISOLATION, AND PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

SATOSHI OMURA, NOBUTAKA IMAMURA, RUIKO OIWA, HIROSHI KUGA, RIMIKO IWATA, ROKURO MASUMA, YUZURU IWAI

著者情報

ジャーナルフリー

1986 年 39 巻 10 号 p. 1407-1412

DOI https://doi.org/10.7164/antibiotics.39.1407

詳細

抄録

A soil isolate named as Micromonospora echinospora subsp. armeniaca subsp. nov. KMR-593 was found to produce at least five related antibiotics, clostomicins, active against Gram-positive bacteria including anaerobes. From the physico-chemical properties, one of these components was identified with lipiarmycin and others were found to be new antibiotics. Each component includes two chlorine atoms and the molecular weights of A and B₂, C, and D are 1, 058, 1, 042 and 1, 056, respectively. The structural differences were characterized by NMR analyses.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）