The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
PALDIMYCINS A AND B AND ANTIBIOTICS 273a2α AND 273a2β
SYNTHESIS AND CHARACTERIZATION
A. D. ARGOUDELIS, L. BACZYNSKYJ, S. A. MIZSAK, F. B. SHILLIDAY, P. A. SPINELLI, J. DEZWAAN
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1987 Volume 40 Issue 4 Pages 419-436

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Abstract
Paldimycin (antibiotic 273a1) and antibiotic 273a2 as well as their individual components, paldimycins A (273a1α) and B (273a1β) and antibiotics 273a2α and 273a2β were synthesized from paulomycin, paulomycin A and paulomycin B, respectively, by reacting with N-acetyl-Lcysteine.
The semisynthetic antibiotics had chromatographic behavior (TLC, HPLC) and physical and chemical properties identical to the properties of the corresponding antibiotics produced by Streptomyces paulus.
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© Japan Antibiotics Research Association
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