The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
BIOSYNTHESIS OF BENASTATIN A
TAKAYUKI AOYAMAHIROSHI NAGANAWAYASUHIKO MURAOKATAKAAKI AOYAGITOMIO TAKEUCHI
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1992 年 45 巻 11 号 p. 1767-1772

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The biosynthesis of benastatin A, produced by Streptomyces sp. MI384-DF12, has been studied by feeding experiments with 14C- and 13C-labeled compounds followed by measurement of radioactivity and 13C NMR analysis. The results indicate that benastatin A is derived from two methionine units and fourteen acetate units, condensed in the "head-to-tail" fashion of typical polyketide biosynthesis.

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© Japan Antibiotics Research Association
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