The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
ISOLATION AND STRUCTURE ELUCIDATION OF NEW ANTIBIOTICS RELATED TO ANGOLAMYCIN
JUDIT KÁDÁR-PAUNCZBENJAMIN PODÁNYIGYULA HORVÁTH
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1992 年 45 巻 8 号 p. 1231-1238

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Angolamycin (1) and two novel analogues (2 and 3) were isolated from the culture broth of a Streptomyces strain. NMR and MS analysis proved that 2 is the 18-dihydro-, while 3 is the 18-deoxo-18-dihydro derivative of angolamycin. Full experimental assignment of the 1H and the 13C NMR spectra of these compounds was obtained from ID and 2D chemical shift correlation measurements. Compounds 2 and 3 are less potent antibiotics than angolamycin.
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© Japan Antibiotics Research Association
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