NEW ANTIVIRAL ANTIBIOTICS, KISTAMICINS A AND B
II. STRUCTURE DETERMINATION
1993 年 46 巻 12 号 p. 1812-1818
詳細
1993 年 46 巻 12 号 p. 1812-1818
The structures of antiviral antibiotics kistamicins A and B have been determined by a combination of chemical degradation and spectral analysis. They are commonly composed of D-tyrosine, 3, 5-dihydrophenylglycine, a biphenyl ether bis-amino acid, and a diphenyl substituted indole tris-amino acid, forming a tricyclic ring structure. Kistamicin B possessed a phenethylamide at the amino terminal of kistamicin A. They are structurally related to the nuclei of the vancornycin group antibiotics particularly to antibiotic complestatin.
