DELAMINOMYCINS, NOVEL EXTRACELLULAR MATRIX RECEPTOR ANTAGONISTS V. BIOSYNTHESIS

MITSUHIRO UENO; IHOMI YOSHINAGA; MASAHIDE AMEMIYA; TETSUYA SOMENO; HIRONOBU IINUMA; MASAAKI ISHIZUAKA; TOMIO TAKEUCHI

doi:10.7164/antibiotics.46.1390

DELAMINOMYCINS, NOVEL EXTRACELLULAR MATRIX RECEPTOR ANTAGONISTS

V. BIOSYNTHESIS

MITSUHIRO UENO, IHOMI YOSHINAGA, MASAHIDE AMEMIYA, TETSUYA SOMENO, HIRONOBU IINUMA, MASAAKI ISHIZUAKA, TOMIO TAKEUCHI

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JOURNAL FREE ACCESS

1993 Volume 46 Issue 9 Pages 1390-1396

DOI https://doi.org/10.7164/antibiotics.46.1390

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Abstract

The biosynthesis of delaminomycin A, produced by Streptomyces albulus MJ202-72F3, was investigated by feeding ¹³C-labeled compounds followed by ¹³C NMR analyses. The results indicate that delaminomycin A is derived from six acetate units, five propionate units and one glycine unit.

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