ALDECALMYCIN, A NEW ANTIMICROBIAL ANTIBIOTIC FROM Streptomyces I. TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

RYUICHI SAWA; YOSHIKAZU TAKAHASHI; SAKIKO ITOH; KAZUO SHIMANAKA; NAOKO KINOSHITA; YOSHIKO HOMMA; MASA HAMADA; TSUTOMU SAWA; HIROSHI NAGANAWA; TOMIO TAKEUCHI

doi:10.7164/antibiotics.47.1266

ALDECALMYCIN, A NEW ANTIMICROBIAL ANTIBIOTIC FROM Streptomyces

I. TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

RYUICHI SAWA, YOSHIKAZU TAKAHASHI, SAKIKO ITOH, KAZUO SHIMANAKA, NAOKO KINOSHITA, YOSHIKO HOMMA, MASA HAMADA, TSUTOMU SAWA, HIROSHI NAGANAWA, TOMIO TAKEUCHI

著者情報

ジャーナルフリー

1994 年 47 巻 11 号 p. 1266-1272

DOI https://doi.org/10.7164/antibiotics.47.1266

詳細

抄録

A new antibiotic, aldecalmycin, has been discovered in the culture broth of Streptomyces sp. MJ147-72F6. Aldecalmycin was purified by solvent extraction, Diaion HP-20 chromatography, silica gel chromatography, Sephadex LH-20 chromatography, HPLC and centrifugal partition chromatography. The ¹H and ¹³C NMR spectra of aldecalmycin showed the presence of keto-enol tautomers. Aldecalmycin is equipotent in inhibiting the growth of sensitive and methicillin-resistant Staphylococcus aureus (MRSA).

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）