Synthesis and Inhibitory Activities of Isochromophilone Analogues against gp120-CD4 Binding

XUE-LONG SUN; HIROAKI TAKAYANAGI; KEIICHI MATSUZAKI; HARUO TANAKA; KIMIO FURUHATA; SATOSHI OMURA

doi:10.7164/antibiotics.49.689

XUE-LONG SUN, HIROAKI TAKAYANAGI, KEIICHI MATSUZAKI, HARUO TANAKA, KIMIO FURUHATA, SATOSHI OMURA

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ジャーナルフリー

1996 年 49 巻 7 号 p. 689-692

DOI https://doi.org/10.7164/antibiotics.49.689

詳細

抄録

Several isochromophilone analogues were synthesized from sclerotiorin (1) by Wittig reactions and aldol condensation reaction. The structures of the products were elucidated from MS, elemental analysis, ¹H NMR and ¹³C NMR spectra, and their inhibitory activities against gp!20-CD4 binding were determined.

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