The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
Inhibitors of Bacterial Signal Peptidase: A Series of 6-(Substituted oxyethyl)penems
AILEEN ALLSOPGERALD BROOKSPETER D. EDWARDSARUN C. KAURAROBERT SOUTHGATE
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1996 年 49 巻 9 号 p. 921-928

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A series of 6-(substituted oxyethyl)penem esters having the (5S) stereochemistry which are potent inhibitors of Escherichia coli leader peptidase is described. Structure-activity relationships are discussed.

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